Yes, and it’s becoming increasingly automated.
Amazon cross-verifies UPC codes with the GS1 database API to confirm that the company prefix matches the brand name in your listing.
If there’s a mismatch, your listing can be suppressed or flagged with the error “Invalid Product ID – Not Matched to Brand.”
This is why barcodes purchased from resellers like Speedy Barcodes often fail during catalog audits or random GS1 checks.